diff --git a/datasette/cli.py b/datasette/cli.py
index bba72484..287195a5 100644
--- a/datasette/cli.py
+++ b/datasette/cli.py
@@ -406,7 +406,7 @@ def serve(
     # Start the server
     if root:
         print("http://{}:{}/-/auth-token?token={}".format(host, port, ds._root_token))
-    uvicorn.run(ds.app(), host=host, port=port, log_level="info")
+    uvicorn.run(ds.app(), host=host, port=port, log_level="info", lifespan="on")
 
 
 async def check_databases(ds):